Following Rafael Juste’s decease, the company experienced considerable growth under the stewardship of Luis and Matilde Juste.
One of the first liver extracts was launched into the market and injected in human clinical trials.
Improved preparation, purification and control techniques led to the development and launch of liver extracts that were increasingly active or combined with other active ingredients.• JUSTE became an ephedrine manufacturer.
The company succeeded in isolating the three main alkaloids in Datura Stramonium: L-hiosciamine, atropine and scopolamine.